shRNA set against Human LBR (NM_194442.2)

Name: shRNA set against Human LBR (NM_194442.2)
SKU: SHH328747
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH328747

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Product Information

Gene Information

Cat. No.	SHH328747
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	LBR
Gene Name	LBR lamin B receptor [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	LBR lamin B receptor [ Homo sapiens ]
Gene Symbol	LBR
Synonyms	LBR; lamin B receptor; lamin-B receptor; DHCR14B; integral nuclear envelope inner membrane protein; PHA; LMN2R; MGC9041; FLJ43126;
Gene ID	3930
Uni Prot ID	Q14739
m RNA Refseq	BC020079
Chromosome Location	1q42.1
Function	DNA binding; chromo shadow domain binding; lamin binding; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; protein binding; receptor activity;
Pathway	Cholesterol biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; cholesterol biosynthesis I, organism-specific biosystem; cholesterol biosynthesis I, conserved biosystem; cholesterol biosynthesis II (via 24,25-dihydrolanosterol), organism-specific biosystem; cholesterol biosynthesis II (via 24,25-dihydrolanosterol), conserved biosystem;
MIM	600024

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