shRNA set against Human KLB (NM_175737.3)

Name: shRNA set against Human KLB (NM_175737.3)
SKU: SHH325643
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH325643

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Gene Information

Cat. No.	SHH325643
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	KLB
Gene Name	KLB klotho beta [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	KLB klotho beta [ Homo sapiens ]
Gene Symbol	KLB
Synonyms	KLB; klotho beta; beta-klotho; betaKlotho; klotho beta like; klotho beta-like protein; BKL; MGC142213;
Gene ID	152831
Uni Prot ID	Q86Z14
m RNA Refseq	BC113653
Chromosome Location	4p14
Function	catalytic activity; cation binding; fibroblast growth factor binding; hydrolase activity, hydrolyzing O-glycosyl compounds;
Pathway	Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem;
MIM	611135

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