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shRNA set against Human KL (NM_004795.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH325631

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Gene Information

Cat. No. SHH325631
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr KL
Gene Name KL klotho [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name KL klotho [ Homo sapiens ]
Gene Symbol KL
GeneID 9365
Uni ProtID Q9UEF7
mRNA Refseq NM_004795.3
Protein Refseq NP_004786.2
Chromosome Location 13q12
Function beta-glucosidase activity; beta-glucuronidase activity; cation binding; fibroblast growth factor binding; fibroblast growth factor receptor binding; hormone activity; signal transducer activity; vitamin D binding;
Pathway Adaptive Immune System, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem;
MIM 604824
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