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shRNA set against Human IRAK4 (NM_016123.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH320533

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Gene Information

Cat. No. SHH320533
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr IRAK4
Gene Name IRAK4 interleukin-1 receptor-associated kinase 4 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name IRAK4 interleukin-1 receptor-associated kinase 4 [ Homo sapiens ]
Gene Symbol IRAK4
Synonyms IPD1; REN64; IRAK-4; NY-REN-64
Gene Description interleukin-1 receptor-associated kinase 4
GeneID 51135
Uni ProtID B4E359
mRNA Refseq NM_001145256.1
Protein Refseq NP_001138728.1
Chromosome Location 12q12
Function ATP binding; interleukin-1 receptor binding; magnesium ion binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;
Pathway Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem;
MIM 606883
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