shRNA set against Human HMBS (NM_000190.3)

Name: shRNA set against Human HMBS (NM_000190.3)
SKU: SHH313193
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH313193

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Gene Information

Cat. No.	SHH313193
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	HMBS
Gene Name	HMBS hydroxymethylbilane synthase [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	HMBS hydroxymethylbilane synthase [ Homo sapiens ]
Gene Symbol	HMBS
Synonyms	UPS; PBGD; PORC; PBG-D
Gene Description	hydroxymethylbilane synthase
GeneID	3145
Uni ProtID	P08397
mRNA Refseq	NM_001024382.1
Protein Refseq	NP_001019553.1
Chromosome Location	11q23.3
Function	amine binding; carboxylic acid binding; coenzyme binding; hydroxymethylbilane synthase activity; uroporphyrinogen-III synthase activity;
Pathway	Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem; heme biosynthesis II, organism-specific biosystem;
MIM	609806

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