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shRNA set against Human GCK (NM_000162.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH300022

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Gene Information

Cat. No. SHH300022
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr GCK
Gene Name GCK glucokinase (hexokinase 4) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name GCK glucokinase (hexokinase 4) [ Homo sapiens ]
Gene Symbol GCK
Synonyms GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3
Gene Description glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
Gene ID 2665
Uni Prot ID P35557
m RNA Refseq NM_000162.3
Protein Refseq NP_000153.1
Chromosome Location 7p15.3-p15.1
Function ADP binding; ATP binding; glucokinase activity; glucose binding; magnesium ion binding; protein binding; protein phosphatase binding;
Pathway Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Butirosin and neomycin biosynthesis, organism-specific biosystem; Butirosin and neomycin biosynthesis, conserved biosystem; Developmental Biology, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; GDP-glucose biosynthesis, organism-specific biosystem;
MIM 138079
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