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shRNA set against Human DOCK2 (NM_004946.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280169

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Gene Information

Cat. No. SHH280169
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DOCK2
Gene Name DOCK2 dedicator of cytokinesis 2 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DOCK2 dedicator of cytokinesis 2 [ Homo sapiens ]
Gene Symbol DOCK2
Synonyms DOCK2; dedicator of cytokinesis 2; dedicator of cyto kinesis 2; dedicator of cytokinesis protein 2; KIAA0209; dedicator of cyto-kinesis 2; FLJ46592;
GeneID 1794
Uni ProtID Q92608
mRNA Refseq BC113457
Chromosome Location 5q35.1
Function GTP binding; GTPase binding; Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; electron carrier activity; guanyl-nucleotide exchange factor activity; heme binding;
Pathway Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Disease, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; HIV Infection, organism-specific biosystem;
MIM 603122
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