Panoply™ Human DOCK2 Knockdown Stable Cell Line

Name: Panoply™ Human DOCK2 Knockdown Stable Cell Line
SKU: CSC-DC004474
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004474

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004474
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DOCK2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DOCK2 dedicator of cytokinesis 2 [ Homo sapiens ]
Gene Symbol	DOCK2
Synonyms	DOCK2; dedicator of cytokinesis 2; dedicator of cyto kinesis 2; dedicator of cytokinesis protein 2; KIAA0209; dedicator of cyto-kinesis 2; FLJ46592;
GeneID	1794
Uni ProtID	Q92608
mRNA Refseq	BC113457
Chromosome Location	5q35.1
Function	GTP binding; GTPase binding; Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; electron carrier activity; guanyl-nucleotide exchange factor activity; heme binding;
Pathway	Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Disease, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; HIV Infection, organism-specific biosystem;
MIM	603122

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