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shRNA set against Human DOCK10 (NM_014689.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH280149

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Gene Information

Cat. No. SHH280149
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DOCK10
Gene Name DOCK10 dedicator of cytokinesis 10 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DOCK10 dedicator of cytokinesis 10 [ Homo sapiens ]
Gene Symbol DOCK10
Synonyms DOCK10; dedicator of cytokinesis 10; dedicator of cytokinesis protein 10; KIAA0694; ZIZ3; zizimin3; zizimin-3; protein zizimin 3; dopamine receptor interacting protein 2; DRIP2; Nbla10300; DKFZp781A1532;
Gene ID 55619
Uni Prot ID Q96BY6
m RNA Refseq BC015018
Chromosome Location 2q36.3
Function GTP binding; GTPase binding; Rho GTPase binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity;
Pathway Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Regulation of CDC42 activity, organism-specific biosystem;
MIM 611518
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