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shRNA set against Human DGKI (NM_004717.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH277509

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Gene Information

Cat. No. SHH277509
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr DGKI
Gene Name DGKI diacylglycerol kinase, iota [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name DGKI diacylglycerol kinase, iota [ Homo sapiens ]
Gene Symbol DGKI
Synonyms DGK-IOTA
Gene Description diacylglycerol kinase, iota
GeneID 9162
Uni ProtID O75912
mRNA Refseq NM_004717.2
Protein Refseq NP_004708.1
Chromosome Location 7q32.3-q33
Function ATP binding; GTPase inhibitor activity; Ras GTPase binding; diacylglycerol kinase activity; metal ion binding; protein binding;
Pathway Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Glycerophospholipid metabolism, organism-specific biosystem;
MIM 604072
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