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shRNA set against Human CYP11A1 (NM_000781.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH272805

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Gene Information

Cat. No. SHH272805
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CYP11A1
Gene Name CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 [ Homo sapiens ]
Gene Symbol CYP11A1
Synonyms CYP11A; CYPXIA1; P450SCC
Gene Description cytochrome P450, family 11, subfamily A, polypeptide 1
GeneID 1583
Uni ProtID P05108
mRNA Refseq NM_000781.2
Protein Refseq NP_000772.2
Chromosome Location 15q23-q24
Function cholesterol binding; cholesterol monooxygenase (side-chain-cleaving) activity; cholesterol monooxygenase (side-chain-cleaving) activity; electron carrier activity; heme binding; iron ion binding;
Pathway Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Endogenous sterols, organism-specific biosystem; Glucocorticoid & Mineralcorticoid Metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
MIM 118485
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