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shRNA set against Human CRP (NM_000567.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH269773

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Gene Information

Cat. No. SHH269773
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CRP
Gene Name CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
Gene Symbol CRP
Synonyms PTX1
Gene Description C-reactive protein, pentraxin-related
GeneID 1401
Uni ProtID P02741
mRNA Refseq NM_000567.2
Protein Refseq NP_000558.2
Chromosome Location 1q21-q23
Function Gram-positive bacterial cell surface binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity;
Pathway Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
MIM 123260
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