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CRP


Official Full Name
C-reactive protein
Organism
Homo sapiens
Gene ID
1401
Background
The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection. [provided by RefSeq, Aug 2020]
Synonyms
PTX1

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LV09785L human CRP (NM_000567) lentivirus particles Inquiry
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SHG200117 shRNA set against Human CRP(NM_000567.2) Inquiry
SHH269773 shRNA set against Human CRP (NM_000567.2) Inquiry
SHG200105 shRNA set against Rat Crp(NM_017096.3) Inquiry
SHG200377 shRNA set against Mouse Crp(NM_007768.4) Inquiry
SHH269777 shRNA set against Mouse CRP (NM_007768.4) Inquiry
SHH269781 shRNA set against Rat CRP (NM_017096.3) Inquiry
SHW002333 shRNA set against Chicken CRP (NM_001039564) Inquiry
SHW010323 shRNA set against Danio rerio CRP (NM_001045860) Inquiry
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CDCB171798 Danio rerio CRP ORF Clone (NM_001045860) Inquiry
CDCL183729 Rat CRP ORF clone(NM_017096.3) Inquiry
CDFH004279 Human CRP cDNA Clone(NM_000567.2) Inquiry
CDFR011162 Rat Crp cDNA Clone(NM_017096.3) Inquiry
MiUTR1H-02437 CRP miRNA 3'UTR clone Inquiry
MiUTR1M-03343 CRP miRNA 3'UTR clone Inquiry
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CDCB156942 Cynomolgus CRP ORF clone Inquiry
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CDCB180230 Rabbit CRP ORF clone (NM_001082265.1) Inquiry
CDCL183727 Human CRP ORF clone(NM_000567.2) Inquiry
CDCL183728 Mouse CRP ORF clone(NM_007768.4) Inquiry
CDCS405751 Human CRP ORF Clone (BC020766) Inquiry
CDCS405752 Human CRP ORF Clone (BC070257) Inquiry
CDCS405753 Human CRP ORF Clone (BC125135) Inquiry
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