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shRNA set against Human CRADD (NM_003805.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH269165

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Gene Information

Cat. No. SHH269165
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CRADD
Gene Name CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Homo sapiens ]
Gene Symbol CRADD
Synonyms MRT34; RAIDD
Gene Description CASP2 and RIPK1 domain containing adaptor with death domain
GeneID 8738
Uni ProtID P78560
mRNA Refseq NM_003805.3
Protein Refseq NP_003796.1
Chromosome Location 12q21.33-q23.1
Function death domain binding; protease binding; protein binding; protein binding, bridging;
Pathway Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Ceramide signaling pathway, organism-specific biosystem; HIV-1 Nef: Negative effector of Fas and TNF-alpha, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
MIM 603454
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