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shRNA set against Human CDC6 (NM_001254.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH259969

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Gene Information

Cat. No. SHH259969
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CDC6
Gene Name CDC6 cell division cycle 6 homolog (S. cerevisiae) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CDC6 cell division cycle 6 homolog (S. cerevisiae) [ Homo sapiens ]
Gene Symbol CDC6
Synonyms CDC18L; HsCDC6; HsCDC18
Gene Description cell division cycle 6 homolog (S. cerevisiae)
GeneID 990
Uni ProtID Q99741
mRNA Refseq NM_001254.3
Protein Refseq NP_001245.1
Chromosome Location 17q21.3
Function ATP binding; chromatin binding; kinase binding; nucleoside-triphosphatase activity; nucleotide binding; protein binding;
Pathway Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; CDK-mediated phosphorylation and removal of Cdc6, organism-specific biosystem; CDT1 association with the CDC6:ORC:origin complex, organism-specific biosystem;
MIM 602627
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