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shRNA set against Human CDC20 (NM_001255.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH259649

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Gene Information

Cat. No. SHH259649
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CDC20
Gene Name CDC20 cell division cycle 20 homolog (S. cerevisiae) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CDC20 cell division cycle 20 homolog (S. cerevisiae) [ Homo sapiens ]
Gene Symbol CDC20
Synonyms CDC20A; p55CDC; bA276H19.3
Gene Description cell division cycle 20 homolog (S. cerevisiae)
Gene ID 991
Uni Prot ID Q12834
m RNA Refseq NM_001255.2
Protein Refseq NP_001246.2
Chromosome Location 1p34.1
Function enzyme binding; protein C-terminus binding; protein binding;
Pathway APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem;
MIM 603618
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