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shRNA set against Human ASCL1 (NM_004316.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH241382

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Gene Information

Cat. No. SHH241382
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ASCL1
Gene Name ASCL1 achaete-scute complex homolog 1 (Drosophila) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name ASCL1 achaete-scute complex homolog 1 (Drosophila) [ Homo sapiens ]
Gene Symbol ASCL1
Synonyms ASH1; HASH1; MASH1; bHLHa46
Gene ID 429
Uni Prot ID P50553
m RNA Refseq NM_004316.3
Protein Refseq NP_004307.2
Chromosome Location 12q23.2
Function DNA binding; E-box binding; bHLH transcription factor binding; double-stranded DNA binding; protein binding; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding transcription factor activity;
Pathway Delta-Notch Signaling Pathway, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
MIM 100790
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