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shRNA set against Human AADAT (NM_182662.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH228578

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Gene Information

Cat. No. SHH228578
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr AADAT
Gene Name AADAT aminoadipate aminotransferase [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name AADAT aminoadipate aminotransferase [ Homo sapiens ]
Gene Symbol AADAT
Synonyms KAT2; KATII
Gene Description aminoadipate aminotransferase
GeneID 51166
Uni ProtID Q4W5N8
mRNA Refseq NM_016228.3
Protein Refseq NP_057312.1
Chromosome Location 4q33
Function 2-aminoadipate transaminase activity; 2-aminoadipate transaminase activity; kynurenine-oxoglutarate transaminase activity; kynurenine-oxoglutarate transaminase activity; protein homodimerization activity; pyridoxal phosphate binding;
Pathway Lysine biosynthesis, organism-specific biosystem; Lysine biosynthesis, conserved biosystem; Lysine catabolism, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Lysine degradation, lysine => saccharopine =>
MIM 611754
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