Recombinant Human PDGFRA (C-6His)

Name: Recombinant Human PDGFRA (C-6His)
SKU: RP00138
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00138 Tag : C-6His

Expressed Region : Gln24-Glu524 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00138
Description	The Recombinant Human PDGFRA (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln24-Glu524 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	57 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Gln24-Glu524
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	PDGFRA
Background	This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Synonyms	Platelet-derived growth factor receptor alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; PDGFR-2; CD140a

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