Recombinant Human IL-21 (C-Fc)

Name: Recombinant Human IL-21 (C-Fc)
SKU: RP00666
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00666 Tag : C-Fc

Expressed Region : Gln30-Ser162 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00666
Description	The Recombinant Human IL-21 (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Gln30-Ser162 with a Fc tag at the C terminus.
Species	Human
Tag	C-Fc
Mol Weight	~45 kDa, on SDS-PAGE under reducing conditions.
Format	Powder
Expressed Region	Gln30-Ser162
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Purity	> 97% as analyzed by SDS-PAGE> 97% as analyzed by HPLC
Endotoxin Level	< 1 EU/μg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	IL21
Background	This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms	IL21; CVID11; IL-21; Za11; interleukin 21

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