ITGAV Easy KO Kit (Human)

Name: ITGAV Easy KO Kit (Human)
SKU: CC-713
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CC-713

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Product Information

Gene Information

Cat. No.	CC-713
Description	A complete kit for efficient gene knockout in mammalian cells, combining chemically synthesized sgRNAs with Cas9 RNPs to induce targeted DNA cleavage and generate frameshift mutations or deletions. All essential reagents for transfection and knockout validation are included for rapid, high-efficiency gene disruption.
Gene Abbr	Itgav
Gene Name	ITGAV integrin, alpha V [ Homo sapiens ]
Species	Human
Ensembl ID	ENSMUSG00000027087
NCBIGene ID	16410
Uni Prot ID	P43406
Features	All-in-One workflow from gene editing to knockout validation for users with no prior experience. Pre-validated sgRNAs and primers for rapid setup. Streamlined experiment handling. CRISPR RNP method ensures precise and efficient gene knockout.
Applications	This kit enables in vitro gene knockout in human-derived cells using chemically synthesized sgRNAs and Cas9-gRNA RNP complexes. Transfected RNPs cleave early exons of the target gene, inducing deletions or frameshift mutations for efficient and rapid knockout.
Reactions	5–10 reactions per target gene
Kit Components	2–3 chemically synthesized sgRNAs (200pmol each) 3 PCR/Sequencing primers (500pmol each) LM cell lysate (500µL) Cas9 protein (12µg) LM RNP transfection reagent (50µL)
Storage	Store at -80°C for up to 1 year or at -20°C for up to 6 months. Avoid repeated freeze-thaw cycles.

Gene Name	ITGAV integrin, alpha V [ Homo sapiens ]
Gene Symbol	ITGAV
Synonyms	CD51; MSK8; VNRA; VTNR
Gene ID	3685
Uni Prot ID	B7Z883
m RNA Refseq	NM_001144999.1
Protein Refseq	NP_001138471.1
Chromosome Location	2q31-q32
Function	contributes_to insulin-like growth factor I binding; contributes_to opsonin binding; protein binding; contributes_to protein kinase C binding; transforming growth factor beta binding; voltage-gated calcium channel activity;
Pathway	Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem;
MIM	193210

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