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Human P2RY2 Nanodisc

For research use only. Not intended for any clinical use.

Cat. No. :   OE-PNDC000541

Tag :   C-Flag tag and Strep Tag Expression System :   Mammalian expression system

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Product Information

Gene Information

Cat. No. OE-PNDC000541
Description Human P2RY2 nanodisc contains full length human P2RY2 protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human P2RY2 protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human P2RY2 membrane protein.
Gene Abbr P2RY2
Gene Name P2RY2
Species Human
Gene Species Human
Tag C-Flag tag and Strep Tag
Features 1) Full-length membrane protein
2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications
3) Maintaining the native spatial conformation and activity of the membrane protein
4) Possessing high solubility and stability
5) High purity determined by HPLC
6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications 1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment.
2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins.
3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins.
4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format Lyophilized protein
Expression System Mammalian expression system
Note For Research Use Only.
Storage Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping Lyophilized proteins are shipped under ambient temperature conditions.
Target Gene P2RY2
Background The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]
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