Human GRIN3A Nanodisc

Name: Human GRIN3A Nanodisc
SKU: OE-PNDC000253
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : OE-PNDC000253

Tag : C-Flag tag and Strep Tag Expression System : Mammalian expression system

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Product Information

Gene Information

Cat. No.	OE-PNDC000253
Description	Human GRIN3A nanodisc contains full length human GRIN3A protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human GRIN3A protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human GRIN3A membrane protein.
Gene Abbr	GRIN3A
Gene Name	GRIN3A
Species	Human
Gene Species	Human
Tag	C-Flag tag and Strep Tag
Features	1) Full-length membrane protein 2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications 3) Maintaining the native spatial conformation and activity of the membrane protein 4) Possessing high solubility and stability 5) High purity determined by HPLC 6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications	1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment. 2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins. 3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins. 4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format	Lyophilized protein
Expression System	Mammalian expression system
Note	For Research Use Only.
Storage	Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping	Lyophilized proteins are shipped under ambient temperature conditions.

Target Gene

GRIN3A

Background

This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]

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