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Human GPRC6A Nanodisc

For research use only. Not intended for any clinical use.

Cat. No. :   OE-PNDC000690

Tag :   C-Flag tag and Strep Tag Expression System :   Mammalian expression system

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Gene Information

Cat. No. OE-PNDC000690
Description Human GPRC6A nanodisc contains full length human GPRC6A protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human GPRC6A protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human GPRC6A membrane protein.
Gene Abbr GPRC6A
Gene Name GPRC6A
Species Human
Gene Species Human
Tag C-Flag tag and Strep Tag
Features 1) Full-length membrane protein
2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications
3) Maintaining the native spatial conformation and activity of the membrane protein
4) Possessing high solubility and stability
5) High purity determined by HPLC
6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications 1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment.
2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins.
3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins.
4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format Lyophilized protein
Expression System Mammalian expression system
Note For Research Use Only.
Storage Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping Lyophilized proteins are shipped under ambient temperature conditions.
Target Gene GPRC6A
Background Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).[supplied by OMIM, Nov 2010]
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