Human CHRNA10 Nanodisc

Name: Human CHRNA10 Nanodisc
SKU: OE-PNDC000274
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : OE-PNDC000274

Tag : C-Flag tag and Strep Tag Expression System : Mammalian expression system

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Product Information

Gene Information

Cat. No.	OE-PNDC000274
Description	Human CHRNA10 nanodisc contains full length human CHRNA10 protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human CHRNA10 protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human CHRNA10 membrane protein.
Gene Abbr	CHRNA10
Gene Name	CHRNA10
Species	Human
Gene Species	Human
Tag	C-Flag tag and Strep Tag
Features	1) Full-length membrane protein 2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications 3) Maintaining the native spatial conformation and activity of the membrane protein 4) Possessing high solubility and stability 5) High purity determined by HPLC 6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications	1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment. 2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins. 3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins. 4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format	Lyophilized protein
Expression System	Mammalian expression system
Note	For Research Use Only.
Storage	Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping	Lyophilized proteins are shipped under ambient temperature conditions.

Target Gene

Chrna10

Background

Enables acetylcholine-gated monoatomic cation-selective channel activity. Acts upstream of or within cholinergic synaptic transmission; detection of mechanical stimulus involved in sensory perception of sound; and inner ear morphogenesis. Predicted to be located in axon and perikaryon. Predicted to be part of transmembrane transporter complex. Predicted to be active in cholinergic synapse; neuron projection; and postsynaptic specialization membrane. Orthologous to human CHRNA10 (cholinergic receptor nicotinic alpha 10 subunit). [provided by Alliance of Genome Resources, Feb 2025]

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