Cbx3 Easy KO Kit (Human)

Name: Cbx3 Easy KO Kit (Human)
SKU: CC-380
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CC-380

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Product Information

Gene Information

Cat. No.	CC-380
Description	A complete kit for efficient gene knockout in mammalian cells, combining chemically synthesized sgRNAs with Cas9 RNPs to induce targeted DNA cleavage and generate frameshift mutations or deletions. All essential reagents for transfection and knockout validation are included for rapid, high-efficiency gene disruption.
Gene Abbr	Cbx3
Gene Name	CBX3 chromobox homolog 3 [ Homo sapiens ]
Species	Human
EnsemblID	ENSMUSG00000029836
NCBIGeneID	12417
Uni ProtID	P23198
Features	All-in-One workflow from gene editing to knockout validation for users with no prior experience. Pre-validated sgRNAs and primers for rapid setup. Streamlined experiment handling. CRISPR RNP method ensures precise and efficient gene knockout.
Applications	This kit enables in vitro gene knockout in human-derived cells using chemically synthesized sgRNAs and Cas9-gRNA RNP complexes. Transfected RNPs cleave early exons of the target gene, inducing deletions or frameshift mutations for efficient and rapid knockout.
Reactions	5–10 reactions per target gene
Kit Components	2–3 chemically synthesized sgRNAs (200pmol each) 3 PCR/Sequencing primers (500pmol each) LM cell lysate (500µL) Cas9 protein (12µg) LM RNP transfection reagent (50µL)
Storage	Store at -80°C for up to 1 year or at -20°C for up to 6 months. Avoid repeated freeze-thaw cycles.

Gene Name	CBX3 chromobox homolog 3 [ Homo sapiens ]
Gene Symbol	CBX3
Synonyms	HECH; HP1-GAMMA; HP1Hs-gamma
GeneID	11335
Uni ProtID	A4D177
mRNA Refseq	NM_007276.4
Protein Refseq	NP_009207.2
Chromosome Location	7p15.2
Function	enzyme binding; identical protein binding; protein binding; protein domain specific binding;
Pathway	Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA Polymerase I Chain Elongation, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem;
MIM	604477

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