Biotinylated Human KDR (C-6His-Avi)

Name: Biotinylated Human KDR (C-6His-Avi)
SKU: RP00627
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00627 Tag : C-6His-Avi

Expressed Region : Ala20-Glu764 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00627
Description	Biotinylated Human KDR (C-6His-Avi) is produced in our Human Cell expression system. The amino acid region expressed is Ala20-Glu764 with a 6His-Avi tag at the C terminus.
Species	Human
Tag	C-6His-Avi
Mol Weight	86.1 KDa
Conjugate	Biotinylated
Format	Powder
Expressed Region	Ala20-Glu764
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	KDR
Background	Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Synonyms	Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1

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