Biotinylated Human IL-2 (C-6His-Avi)

Name: Biotinylated Human IL-2 (C-6His-Avi)
SKU: RP00423
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00423 Tag : C-6His-Avi

Expressed Region : Ala21-Thr153 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00423
Description	The Biotinylated Human IL-2 (C-6His-Avi) is produced in our Human Cell expression system. The amino acid region expressed is Ala21-Thr153 with a 6His-Avi tag at the C terminus.
Species	Human
Tag	C-6His-Avi
Mol Weight	18.3 KDa
Conjugate	Biotinylated
Format	Powder
Expressed Region	Ala21-Thr153
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	IL2
Synonyms	Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

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This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

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