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Human FCGR1A/NFAT-Luc Stable Cell Line - Jurkat

Human FCGR1A/NFAT-Luc Stable Cell Line - Jurkat

Cat.No. :  CSC-RO01139 Host Cell:  Jurkat

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Cell Line Information

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Cat. No. CSC-RO01139
Description This cell line is engineered to constitutively overexpress human FCGR1A, and luciferase reporter gene under the control of NFAT response element. This cell line can be used to evaluate ADCP (antibody-dependent cellular phagocytosis) activity of antibodies in the presence of corresponding target cells.
Gene FCGR1A/NFAT-Luc
Gene Species Homo sapiens (Human)
Host Cell Jurkat
Host Cell Species Homo sapiens (Human)
Stability Validated for at least 10 passages
Application

1. Development and evaluation of monoclonal antibodies (mAbs)

2. Development of antibody-based immunotherapies

3. Vaccine development

4. Infectious disease treatment

Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Shipping Dry ice
Storage Liquid nitrogen
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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