CLU Alzheimer's Disease Risk Genotyping Kit

Name: CLU Alzheimer's Disease Risk Genotyping Kit
SKU: GK-0005
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : GK-0005

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Product Information

Cat. No.	GK-0005
Description	Leveraging two major technology platforms—KASP (Kompetitive Allele-Specific PCR) and TaqMan MGB probes—we provide cost-effective or ultra-high-specificity custom genotyping services for any species and any genetic locus.
Introduction	If the customer provides a specific genotyping RS number, we can perform custom development and offer SNP testing services upon receipt of mailed blood/tissue/cell samples. The customer needs to provide: 1. Sample materials such as cells (≥10^6 cells), tissue (≥300 mg), blood (≥1 ml), serum (≥1.5 ml), etc.; nucleic acid extraction is charged separately; 2. Genomic DNA (volume ≥30 μl, concentration ≥50 ng/μl), with purity OD260/280 between 1.7 and 1.9; 3. For the human genome, the RS number of the SNP locus must be provided. For other species without rs numbers, such as cattle, chickens, and fish, the exact 200 bp sequences flanking both upstream and downstream of the SNP locus must be provided, along with the mutation type at the SNP locus and whether any other linked loci exist within 25 bp upstream or downstream of the locus. We deliver: 1. SNP results (Excel spreadsheet); 2. Complete experimental report: amplification and reaction systems, primers involved, and probe sequences; Scatter plot of clustering results (KASP method) / Amplification curves and Ct value analysis (TaqMan MGB method). 3. Other relevant materials required by the customer.
Gene	CLU
Features	Genotyping Accuracy >99%
Applications	Research Use
Size	Box
Format	100T
Note	All SNP kits are custom-developed and not available from stock. Primers and probes are individually designed and synthesized based on the RS numbers or target sequences provided by the customer.
Storage	-20℃

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The CLU gene (apolipoprotein J gene) is one of the most influential risk genes in Alzheimer's disease genetic research. Its specific locus genetic variation has been repeatedly validated by multiple large-scale international studies and is significantly associated with the risk of late-onset Alzheimer's disease, with a stable effect independent of classic APOE genotype status, making it a globally recognized core genetic marker for Alzheimer's disease. Detection of this locus helps individuals understand their own genetic susceptibility and provides a scientific reference for early risk screening, health management, and intervention strategy development. It can also serve as an important tool for genetic risk assessment of Alzheimer's disease in scientific research, and holds significant clinical application value and public health significance for promoting early disease identification, risk stratification, and precision prevention. However, it should be noted that the test result only reflects a genetic risk tendency and cannot be used as a basis for disease diagnosis; it should be comprehensively evaluated in combination with clinical symptoms, imaging examinations, and other biomarkers.

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