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TCF-LEF/Luciferase Reporter Stable Cell Line-HEK293

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Cat.No.
CSC-RR0084
Introduction
The Wnt pathway controls a large and diverse set of cell fate decisions in embryonic development, adult organ maintenance and disease. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to stabilization and nuclear translocation of beta-catenin. beta-catenin then binds to TCF/LEF transcription factors in the nucleus, leading to transcription and expression of Wnt responsive genes.
Keywords
Wnt; Wnt signaling pathway; wnt; Pfam: PF00110; InterPro:IPR005817; PROSITE: PDOC00219; TCF/LEF;
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice

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