S100P Validated sgRNA vector

Name: S100P Validated sgRNA vector
SKU: SKO0948
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SKO0948

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Product Information

Vector Map

Gene Information

Cat. No.	SKO0948
Description	Creative Biogene develops and optimizes genome editing technology to produce stable genome edited mammalian cell lines serving a wide-range of R&D activities in areas of basic research, diagnostic and therapeutic development. Our premade SuperKO sgRNA vectors are tailor-made to target many different genes respectively. We have successfully constructed a series of knockout cell lines using those sgRNAs.
Gene Abbr	S100P
Reporter	mCherry
Promoter	U6
Resistance	Amp
Selection	Ampicillin
Vector Type	Lentiviral Expression
Vector Length	7677 bp

Target Gene

S100P

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]

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