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Rat Zbtb20 cDNA Clone(NM_001105880.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005611

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Gene Information

Cat. No. CDFR005611
Description NativeORF clone of Rattus norvegicus zinc finger and BTB domain containing 20 (Zbtb20) as transfection-ready DNA NM_001105880.1
Product Type cDAN Clone
Gene Abbr Zbtb20
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ZBTB20
Background This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
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