Rat Ythdf2 cDNA Clone(NM_001047099.1)

Name: Rat Ythdf2 cDNA Clone(NM_001047099.1)
SKU: CDFR004842
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004842

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Product Information

Gene Information

Cat. No.	CDFR004842
Description	NativeORF clone of Rattus norvegicus YTH domain family, member 2 (Ythdf2) as transfection-ready DNA NM_001047099.1
Product Type	cDAN Clone
Gene Abbr	Ythdf2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

YTHDF2

Background

This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]

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