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Rat Wwp1 cDNA Clone(NM_001024757.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003660

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Gene Information

Cat. No. CDFR003660
Description NativeORF clone of Rattus norvegicus WW domain containing E3 ubiquitin protein ligase 1 (Wwp1) as transfection-ready DNA NM_001024757.1
Product Type cDAN Clone
Gene Abbr Wwp1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene WWP1
Background WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
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