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Rat Wdr73 cDNA Clone(NM_001107525.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007214

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Gene Information

Cat. No. CDFR007214
Description NativeORF clone of Rattus norvegicus WD repeat domain 73 (Wdr73) as transfection-ready DNA NM_001107525.2
Product Type cDAN Clone
Gene Abbr Wdr73
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene WDR73
Background The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
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