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Rat Wasf1 cDNA Clone(NM_001025114.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003842

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Gene Information

Cat. No. CDFR003842
Description NativeORF clone of Rattus norvegicus WAS protein family, member 1 (Wasf1) as transfection-ready DNA NM_001025114.1
Product Type cDAN Clone
Gene Abbr Wasf1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene WASF1
Background The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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