Pages
Products

Rat Vps33a cDNA Clone(NM_022961.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012184

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR012184
Description NativeORF clone of Rattus norvegicus vacuolar protein sorting 33 homolog A (S. cerevisiae) (Vps33a) as transfection-ready DNA NM_022961.3
Product Type cDAN Clone
Gene Abbr Vps33a
Species Rat
Vector pCMV6Entry
Target Gene VPS33A
Background This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) complex, perform diverse functions in endocytosis including membrane tethering, RabGTPase interaction, activation and proofreading of synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) assembly to drive membrane fusion, and endosome-to-cytoskeleton attachment. The HOPS complex controls endosome maturation as well as endosome traffic to the lysosome. This complex is essential for vacuolar fusion and is required for adaptor protein complex 3-dependent transport from the golgi to the vacuole. The encoded protein belongs to the Sec1/Munc18 (SM) family of SNARE-mediated membrane fusion regulators. Naturally occurring mutations in this gene are associated with a novel mucopolysaccharidosis-like disease. [provided by RefSeq, Apr 2017]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction