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Rat Vmp1 cDNA Clone(NM_138839.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014266

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Gene Information

Cat. No. CDFR014266
Description NativeORF clone of Rattus norvegicus transmembrane protein 49 (Tmem49) as transfection-ready DNA NM_138839.2
Product Type cDAN Clone
Gene Abbr Vmp1
Species Rat
Vector pCMV6Entry
Target Gene VMP1
Background This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016]
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