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Rat Vcp cDNA Clone(NM_053864.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013594

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Gene Information

Cat. No. CDFR013594
Description NativeORF clone of Rattus norvegicus valosin-containing protein (Vcp) as transfection-ready DNA NM_053864.2
Product Type cDAN Clone
Gene Abbr Vcp
Species Rat
Vector pCMV6Entry
Target Gene VCP
Background This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]
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