Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR007222
| Cat. No. | CDFR007222 |
| Description | NativeORF clone of Rattus norvegicus UV radiation resistance associated gene (Uvrag) as transfection-ready DNA NM_001107536.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Uvrag |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | UVRAG |
| Background | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008] |
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