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Rat Usp14 ORF Clone(NM_001008301.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR368830

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Gene Information

Cat. No. CDCR368830
Product Type ORF Clone
Gene Abbr Usp14
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1482 bp
Vector pCMV6-Entry
Target Gene USP14
Background This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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