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Rat Upk1b cDNA Clone(NM_001024253.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003527

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Gene Information

Cat. No. CDFR003527
Description NativeORF clone of Rattus norvegicus uroplakin 1B (Upk1b) as transfection-ready DNA NM_001024253.1
Product Type cDAN Clone
Gene Abbr Upk1b
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene UPK1B
Background The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
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