Pages
Products

Rat Unc45b cDNA Clone(NM_001107028.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006740

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR006740
Description NativeORF clone of Rattus norvegicus unc-45 homolog B (C. elegans) (Unc45b) as transfection-ready DNA NM_001107028.1
Product Type cDAN Clone
Gene Abbr Unc45b
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene UNC45B
Background This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction