Rat Ugt1a8 cDNA Clone(NM_175846.2)

Name: Rat Ugt1a8 cDNA Clone(NM_175846.2)
SKU: CDFR014879
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014879

Inquire for Price

Product Information

Gene Information

Cat. No.	CDFR014879
Description	NativeORF clone of Rattus norvegicus UDP glycosyltransferase 1 family, polypeptide A8 (Ugt1a8) as transfection-ready DNA NM_175846.2
Product Type	cDAN Clone
Gene Abbr	Ugt1a8
Species	Rat
Vector	pCMV6Entry

Target Gene

UGT1A8

Background

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids. [provided by RefSeq, Jul 2008]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *