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Rat Ucn3 cDNA Clone(NM_001080208.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005057

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Gene Information

Cat. No. CDFR005057
Description NativeORF clone of Rattus norvegicus urocortin 3 (stresscopin) (Ucn3) as transfection-ready DNA NM_001080208.1
Product Type cDAN Clone
Gene Abbr Ucn3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene UCN3
Background This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016]
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