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Rat Ubqln1 ORF Clone(NM_053747.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380397

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Gene Information

Cat. No. CDCR380397
Product Type ORF Clone
Gene Abbr Ubqln1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1749 bp
Vector pCMV6-Entry
Target Gene UBQLN1
Background This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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