Rat Ube2d2 cDNA Clone(NM_001037292.1)

Name: Rat Ube2d2 cDNA Clone(NM_001037292.1)
SKU: CDFR004506
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004506

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Product Information

Gene Information

Cat. No.	CDFR004506
Description	NativeORF clone of Rattus norvegicus ubiquitin-conjugating enzyme E2D 2 (Ube2d2) as transfection-ready DNA NM_001037292.1
Product Type	cDAN Clone
Gene Abbr	Ube2d2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

UBE2D2

Background

Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

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