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Rat Ube2b ORF Clone(NM_031138.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379630

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Gene Information

Cat. No. CDCR379630
Product Type ORF Clone
Gene Abbr Ube2b
Species Rat
Tag C-terminal Myc-DDK
ORF Size 459 bp
Vector pCMV6-Entry
Target Gene UBE2B
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]
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