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Rat Tsn ORF Clone(NM_021762.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378816

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Product Information

Gene Information

Cat. No. CDCR378816
Product Type ORF Clone
Gene Abbr Tsn
Species Rat
Tag C-terminal Myc-DDK
ORF Size 687 bp
Vector pCMV6-Entry
Target Gene TSN
Background This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
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